• PL-METAX-V10
1 1

Investigational triple-receptor agonist research peptide

META-X Retatrutide

META-X Retatrutide

Retatrutide (LY3437943)

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Strength

Retatrutide is an investigational acylated peptide used in laboratory research on combined glucagon, GLP-1 and GIP receptor signaling.

Specifications

Active material
Retatrutide (LY3437943)
Available variant(s)
10 mg and 20 mg
Form
Lyophilized powder
Container
3 mL vial
CAS number(s)
2381089-83-2 (parent identifier; counter-ion must match the COA)
Molecular formula
C221H342N46O68 (parent representation)
Molecular weight
4731.3 g/mol (parent; sodium content may alter the exact mass)
Sequence / structure
39-residue acylated synthetic peptide with non-natural residues and a lipid side chain

What this material is studied for
  • GCGR, GLP-1R and GIPR receptor pharmacology and cAMP signaling assays.
  • Multi-agonist structure-activity and receptor-bias studies.
  • Metabolic signaling studies in validated cell and preclinical models.

Scientific context

Retatrutide acts as an agonist at the glucagon receptor, the GLP-1 receptor and the GIP receptor. Its lipid modification supports albumin binding in clinical-development formulations, but this catalogue does not imply equivalence between those formulations and the Peptiva research vial.

Storage and handling

Store according to the product label instructions. Protect from light. Keep sealed until research use.

Disclaimer

For laboratory research use only. Not for human or veterinary use. Not a food, drug, cosmetic or dietary supplement. Not intended to diagnose, treat, cure or prevent any disease. Purchasers are responsible for lawful handling and use by qualified personnel.

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