• PL-MITOX-P40
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Mitochondrial-derived peptide research material

MITO-X MOTS-C Research Pen

MITO-X MOTS-C Research Pen

MOTS-c (mitochondrial open reading frame of the 12S rRNA-c)

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Strength

MOTS-c is a 16-amino-acid mitochondrial-derived peptide used in laboratory research on cellular energy sensing, AMPK-linked pathways and mitochondrial-to-nuclear signaling. The supplied artwork declares one 3 mL pre-filled research pen containing 40 mg total.

Specifications

Active material
MOTS-c (mitochondrial open reading frame of the 12S rRNA-c)
Declared presentation
40 mg total per pen
Container
3 mL nominal cartridge, one pre-filled pre-mixed pen
Nominal concentration
13.33 mg/mL nominal (40 mg / 3 mL)
CAS number(s)
1627580-64-6
Molecular formula
C101H152N28O22S2 for the free peptide
Molecular weight
2174.6 g/mol free peptide; the mono-trifluoroacetate form is listed elsewhere at 2288.6 g/mol
Sequence / structure
Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (MRWQEMGYIFYPRKLR)
Synonyms
MOTS-c; human MOTS-c; mitochondrial-derived peptide

What this material is studied for
  • AMPK-linked cellular energy-sensing and purine-metabolism research.
  • Mitochondrial-to-nuclear signaling and stress-adaptation models.
  • Glucose-utilization and skeletal-muscle metabolic-pathway studies.

Scientific context

MOTS-c is encoded within the mitochondrial 12S rRNA region and has been investigated primarily in cell and animal models involving purine metabolism, AICAR accumulation, AMPK activation, glucose utilization, stress adaptation and metabolic homeostasis.

Storage and handling

Store a mixed or in-use research pen refrigerated at 2–8 °C (36–46 °F). Keep unused pens cold until their expiry date, protect them from direct light, and never freeze them.

Disclaimer

For laboratory research use only. Not for human or veterinary use. Not a food, drug, cosmetic or dietary supplement. Not intended to diagnose, treat, cure or prevent any disease. Purchasers are responsible for lawful handling and use by qualified personnel.

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